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Genome Biology Program |
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GOALS |
The goals of the Genome Biology Program (GBP) is to understand the structure and function of various microorganisms and microbial communities and elucidate the evolutionary dynamics that shape their genomes. To accomplish that members of the program are developing pipelines for processing sequencing data, as well as methods and toolkits that facilitate their own genome analysis efforts and support those of the scientific community at large. |
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PROJECTS |
The ongoing projects of the Genome Biology program include (a) the development of large scale data integration systems for comparative analysis, annotation and interpretation of isolate genomes and metagenomes, such as the Integrated Microbial Genome systems (IMG and IMG/M); (b) the development and application of fully automated annotation pipelines (i.e. gene and function prediction) for isolate genomes and metagenomes; (c) the development and application of pipelines for evaluating the quality of the automated gene predictions and their correction (Gene models Quality Control); (d) the development and curation of control vocabularies for the representation of gene function and their pathways (IMG Terms and Pathways) which significantly improves the speed and accuracy of gene annotation and genome interpretation; (e) the development and application of tools for processing and analyzing microbial communities sequenced with various technology platforms (i.e. both Sanger and 454 technologies), and others. The Genome Biology Program also has a major research interest and focus on BioEnergy with ongoing research activities on (a) archaeal genomics and methane production, (b) genomics of microorganisms and communities that decompose plant biomass and (c) bioengineering of lipid metabolism for biodiesel production. |
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